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The COC Protocol is an individualised therapeutic approach which seeks to simultaneously target multiple cancer pathways. It is a proprietary combination of conventional pharmaceuticals which may work together to restrict the overall ability of cancer cells to take up and use (i.e., ‘metabolise’) energy. Its explained far better than I ever could put into words here.
We first heard about Care Oncology through forums and what other patients and caregivers told us. We approached Stus original medical team during one of his first meetings but were greeted with eye rolls from one of the doctors. We did a lot of reading about Care Oncology and spoke to a lot of patients before contacting them.
They are now providing a blood monitoring service to assess the metabolic and inflammatory status so they can make recommendations to optimise your protocol.
While on the protocol you have consultations with their doctors every quarter and they are now offering additional support from their experienced metabolic oncologists to review your results, your personal protocol and provide guidance on nutrition, supplements, exercise, sleep and stress.
The initial consultation was £450.
Follow up appointments are £225.
The first one is 8 weeks after commencing treatment and the others are quarterly.
The first 8 weeks was approx £60 and then 3 months was £116
We wish Stu had started this from the very beginning to start alongside radiotherapy and chemotherapy. The author Jane McLelland writes about Care Oncology in her book and the theory behind it is also part of Dr Ben Williams book (he's a long term GBM survivor) about how some re-purposed medications enhance the standard of care treatments.
Dr Kuhan was so helpful and personable so the consultations with him were easy to understand, you could ask any questions you had and felt like you have another doctor on the team.
METFORMIN - Induces decreased proliferation, cell cycle arrest, autophagy, apoptosis, and cell death in-vitro. Desmoplasia – Hostile tumor microenvironment.
ATORVASTIN - Cytotoxic effect to glioma cells. Similar to temozolomide, it could reduce the migration and proliferation of tumor cells, with no toxicity to astrocytes. Atorvastatin inhibits NFKB activation.
MEBENDAZOLE - Micro-tubal destabiliser, cytotoxic to cancer cells, mitochondrial translocation of p53, inhibits glucose, uptake, expression of GLUT transporters & hexokinase.
DOXYCYCLINE - Shown to help block tumour cell growth and division, and to reduce glioma cells' potential to move and invade other areas of the body.
You can read about the COC protocol specifically for Gliomas here.
There is a really useful private Facebook group where you can keep up to date with other patients and see the updates as they happen.
All data collected is part of a clinical trial you can read about their GBM results so far here.
What is Care Oncology?
In their own words:
The Care Oncology Clinic offers a supervised treatment regimen (the COC Protocol) for people diagnosed with cancer of any type or stage. Developed by scientists and oncologists, the COC Protocol is intended for adjunctive administration alongside standard-of-care therapy.
It involves a multipronged approach, supported by peer-reviewed scientific studies, which highlight the potential of certain treatments to target the energy requirements of cancer cells.
The COC Protocol may:
- Improve your response to standard-of-care therapies (chemotherapy, immunotherapy, hormonal, and radiotherapies)
- Reduce side effects from your current cancer treatment
- Enable a process called apoptosis, or “programmed cell death,” of cancer cells
- Return your body back to a healthy metabolic and inflammatory state following cancer treatment to help minimise recurrence.